A new type of cable sealing assembly discloses a unilateral hole waterproof sealing assembly for pipe insertion connection, which includes an elastic sealing sleeve, a bottom sealing cover and a bottom plug sleeved at the bottom end of the pipe. The bottom plug is located at the edge of the opening of the unilateral hole. The elastic sealing sleeve includes an extrusion sealing part pressed between the outer wall of the pipe and the inner wall of the bottom plug. The second extrusion sealing part around the single side hole and the connecting part connecting the extrusion sealing part and the second extrusion sealing part are pressed by the bottom plug cover. The utility model has the advantages of simple and compact structure, low cost, good sealing performance and stable installation. The core component of the product of the inflatable cable pipeline sealing device (IDSS) is "inflatable pipe plug", which is made of high polymer aluminum foil composite material. The inflatable pipe is covered with waterproof tape on both sides. The inflatable pipe plug is filled with silica gel material. The self-filling property of silica gel material can seal and extract the inflatable hole. With a non-fixed inflatable tube, the inflatable tube can be pulled out. It is a new type of cable pipeline sealing device, which is specially used to plug the pipe opening of the cable-related sleeve.